ML Algorithms in Healthcare

A comprehensive guide to machine learning applications in medical practice and clinical decision support

Linear Regression
✅ Pros
Simple and highly interpretable. Requires minimal computational power. Provides clear coefficient relationships.
❌ Cons
Assumes linear relationship between features and target. Sensitive to outliers and multicollinearity.
🎯 Healthcare Applications
Predicting patient recovery times, drug dosage optimization, cost forecasting for treatments.
Estimating blood pressure based on age and BMI, predicting hospital length of stay, modeling medication effectiveness over time, forecasting healthcare costs.
📋 Summary
Models linear relationships between medical variables and outcomes for predictive healthcare analytics and resource planning.
Logistic Regression
✅ Pros
Simple, fast, and interpretable. Provides probability scores for outcomes. Handles categorical variables well.
❌ Cons
Assumes linear decision boundary. May be outperformed by more complex models for non-linear relationships.
🎯 Healthcare Applications
Disease diagnosis, treatment success prediction, patient risk assessment, screening tests.
Diabetes screening, heart attack risk prediction, cancer detection from biomarkers, surgical outcome prediction, patient readmission risk.
📋 Summary
Predicts probability of binary medical outcomes (disease/no disease, success/failure) with interpretable coefficients.
Decision Trees
✅ Pros
Easy to understand and visualize. Can handle both numerical and categorical data. No assumptions about data distribution.
❌ Cons
Prone to overfitting. Can become overly complex. Sensitive to small changes in data.
🎯 Healthcare Applications
Clinical decision support, diagnostic pathways, treatment selection, patient triage.
Symptom-based diagnosis trees, treatment protocol selection, patient triage systems, medical guideline automation, risk stratification.
📋 Summary
Creates interpretable decision pathways that mirror clinical reasoning processes and medical decision trees.
Random Forest
✅ Pros
Robust to overfitting. Can handle large datasets with high dimensionality. Provides feature importance rankings.
❌ Cons
Less interpretable compared to single decision tree. Requires more computational power. Can be slow for real-time applications.
🎯 Healthcare Applications
Complex diagnostic tasks, ensemble predictions, biomarker discovery, electronic health record analysis.
Multi-disease risk assessment, genomic data analysis, drug discovery, EHR pattern recognition, medical image classification.
📋 Summary
Combines multiple decision trees for robust predictions in complex healthcare scenarios with built-in feature selection.
Naive Bayes
✅ Pros
Fast training and prediction. Works well with small datasets. Handles missing data gracefully. Provides probability estimates.
❌ Cons
Assumes feature independence (naive assumption). May not capture complex relationships between variables.
🎯 Healthcare Applications
Disease classification, text analysis of medical reports, spam detection in medical communications, risk assessment.
Medical document classification, symptom-based disease prediction, patient email triage, medical literature analysis, clinical text mining.
📋 Summary
Probabilistic classifier based on Bayes theorem, excellent for text analysis and medical document processing.
Support Vector Machines
✅ Pros
Effective in high dimensional spaces. Provides clear margin of separation. Robust to overfitting with proper regularization.
❌ Cons
Less effective on large datasets. Requires careful kernel choice and parameter tuning. Computationally intensive.
🎯 Healthcare Applications
High-precision classification, especially when classes are closely related or data is high-dimensional.
Cancer subtype classification, protein structure prediction, medical text categorization, gene expression analysis, biomarker classification.
📋 Summary
Finds optimal boundaries between different medical conditions or patient groups using sophisticated mathematical optimization.

© 2025 Machine Learning for Health Research Course | Prof. Gennady Roshchupkin

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