Bias measures how far off our model's predictions are from the true values on average. High bias means the model is too simple and misses important patterns in the data.
Variance measures how much our model's predictions change when trained on different datasets. High variance means the model is too sensitive to small changes in training data.
This fundamental equation shows that prediction error comes from three sources: systematic bias, model variance, and inherent noise in the data.
As model complexity increases, bias typically decreases while variance increases. The goal is finding the optimal balance.
High Bias
Low Variance
Underfitting
Balanced Bias
Balanced Variance
Good Generalization
Low Bias
High Variance
Overfitting
© 2025 Machine Learning for Health Research Course | Prof. Gennady Roshchupkin
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